Opportunity Information: Apply for PAS 18 483
The Promoting Research in Basic Neuroscience (R01) opportunity (Funding Opportunity Number PAS 18 483) is a National Institutes of Health (NIH) research grant designed to support investigator-driven projects that tackle core, foundational questions in neuroscience. Its central purpose is to move the field forward by deepening what we know about how the normal nervous system develops, how it is built and organized, and how it works at different levels of analysis. The emphasis is on basic neuroscience rather than applied or clinical work, meaning proposals should be framed around discovering fundamental principles, mechanisms, and functions that govern nervous system biology.
Projects proposed under this announcement may cover essentially any area of neuroscience, as long as the topic aligns with the missions of the NIH institutes participating in the announcement. Applicants are encouraged to focus on studies that illuminate the development of neural systems, the structure of neural circuits and cell types, and the functions that emerge from neural activity and organization. The scope is intentionally broad so that researchers can pursue a wide range of questions, from molecular and cellular neuroscience through systems and circuit neuroscience and other fundamental approaches, provided the work is aimed at understanding the normal nervous system.
A key boundary in this announcement is that it is not meant to fund research that is explicitly disease-related. The NIH notes that basic research often ends up being relevant to neurological or psychiatric disorders, and that kind of downstream relevance is not a problem. However, applications should not be written around specific diseases, disorder mechanisms, or therapeutic goals as the main driver. In practical terms, this means the rationale, aims, and outcomes should be centered on normal neural development, structure, and function, rather than on diagnosing, treating, or directly explaining a particular disorder.
This is a discretionary grant mechanism under the R01 activity code, which generally supports substantial, multi-year research projects led by an investigator (or team) with a defined set of aims. The opportunity falls under the Health funding activity category and is associated with CFDA number 93.853. The agency listed is the U.S. Department of Health and Human Services, National Institutes of Health, reflecting that NIH is the funding body and that applications are expected to follow NIH standards and expectations for research grants.
Eligibility is broad and includes many types of domestic organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and additional entities as allowed under the announcement’s eligibility clarification text. In short, the program is open to a wide range of academic, governmental, nonprofit, and private-sector research organizations capable of carrying out basic neuroscience research.
In terms of timing and scale, the record shows a creation date of December 8, 2017, with an original closing date of January 7, 2021. The expected number of awards is listed as 12. The award ceiling is shown as 0, which typically indicates that a specific upper limit is not stated in the listing and that budget expectations are instead governed by NIH policies, the R01 mechanism norms, institute-specific practices, and the project’s justified needs.
Overall, this FOA is best understood as a broad invitation for scientists to propose rigorous, hypothesis-driven (or otherwise strongly justified) studies that reveal how the healthy nervous system is formed and how it operates. Competitive applications under this announcement would generally be expected to make a clear case for fundamental significance to neuroscience, present strong conceptual framing and methodology, and avoid positioning the work as a direct investigation of a particular disease, even if the discoveries could eventually inform disease understanding later on.Apply for PAS 18 483
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Promoting Research in Basic Neuroscience (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
- This funding opportunity was created on Dec 08, 2017.
- Applicants must submit their applications by Jan 07, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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