Opportunity Information: Apply for RFA HD 18 028
The funding opportunity titled "Point of Care Technologies for the Evaluation and Management of Obstetrics, Neonatal, and Pediatric Critical Care Patients, and for Patients with Disorders of Reproductive Tract and Infertility (R43)" is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant solicitation focused on advancing point-of-care (POC) tools that can be used directly in clinical environments to improve real-time decision-making. It is identified as RFA HD 18 028, falls under the discretionary grant category, and is listed under CFDA 93.865. The overall intent is to accelerate early-stage small business research that either creates new POC diagnostic or monitoring devices or adapts and implements existing cutting-edge technologies so they can be deployed effectively in real clinical settings where obstetric, neonatal, pediatric critical care, or reproductive health decisions must often be made quickly and with incomplete information.
The scientific and product development emphasis is on advanced technology approaches that can shrink complex laboratory-type capabilities into fast, usable, near-patient formats. The FOA explicitly highlights technology examples such as bio-chips, microfluidics, and mobile technologies, which signals an interest in miniaturized assays, lab-on-a-chip platforms, smartphone-enabled diagnostics, portable sensors, and other solutions that can deliver actionable results at or near the bedside. In practical terms, this can include tools that help clinicians diagnose conditions faster, monitor patient status continuously or intermittently with minimal burden, stratify risk, guide therapy selection or dosing, and track response to treatment. The focus on implementing existing technologies in clinical settings also suggests NIH is interested not only in new inventions, but also in translational work that addresses workflow integration, usability, reliability, and performance in real-world care environments.
The patient populations and clinical use cases targeted by this grant are clearly defined and span several high-need areas. On the maternal and obstetric side, the opportunity supports POC technologies relevant to pregnancy, labor and delivery, and maternal complications where rapid assessment can influence outcomes. In neonatal and pediatric critical care, the emphasis is on technologies that can support critically ill infants and children, where sample volumes are small, physiology changes quickly, and delays in diagnosis or treatment can have outsized consequences. The FOA also covers patients with disorders of the reproductive tract and infertility, which broadens the scope to include diagnostics and monitoring tools that can inform evaluation and management of reproductive health conditions, fertility assessment, and infertility treatment pathways. Across these areas, the common theme is that faster and more accessible diagnostic or monitoring information can directly guide clinical decisions and improve management.
From an applicant eligibility perspective, the FOA is aimed at small businesses, consistent with the SBIR R43 mechanism, which is generally used to support Phase I feasibility research and early proof-of-concept work. The eligible applicant category listed is small businesses, and the program is administered by NIH. The opportunity explicitly restricts foreign participation at the applicant organization level: non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, it notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed, meaning a U.S. small business might be able to include certain types of foreign collaborations or activities if they meet NIH policy definitions and are justified, but the primary applicant must remain a qualifying U.S. small business and the main work cannot be structured as a non-domestic component of the organization.
Key administrative details included in the source information are that the agency is the National Institutes of Health, the funding instrument type is a grant, and the original closing date was June 30, 2017, with a creation date of April 13, 2017. The listing does not provide an award ceiling or expected number of awards in the provided fields, which typically means applicants would need to consult the full announcement text for budget guidance, project period expectations, and the number or size of anticipated awards. Overall, this FOA is best understood as an NIH SBIR initiative encouraging small businesses to build and translate POC technology platforms that can materially improve diagnostic and therapeutic management for high-risk maternal, newborn, pediatric, and reproductive health populations, especially in settings where timely, reliable data at the point of care can change clinical outcomes.Apply for RFA HD 18 028
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Point of Care Technologies for the Evaluation and Management of Obstetrics, Neonatal, and Pediatric Critical Care Patients, and for Patients with Disorders of Reproductive Tract and Infertility (R43)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on 2017-04-13.
- Applicants must submit their applications by 2017-06-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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