Opportunity Information: Apply for NV VSR 21 001
The grant opportunity titled Promoting Vaccine Confidence in Local Communities through Partnership with Regional Health Offices is a Fiscal Year 2021 funding announcement from the U.S. Department of Health and Human Services (HHS), issued through the Office of the Assistant Secretary for Health (OASH), specifically the Office of Infectious Disease and HIV/AIDS Policy (OIDP). It is offered under the legal authority of sections 1702 and 1703 of the Public Health Service Act (42 U.S.C. 300u-1 and 300u-2) and is structured as a cooperative agreement, meaning the federal government expects to be actively involved with recipients during the project rather than simply issuing a one-time award and stepping back.
At a practical level, the program is built around the idea that vaccines only deliver their full public health benefit when communities actually accept and use them at high enough levels to maintain broad immunity. OIDP, which oversees the National Vaccine Program, frames vaccine confidence as a central ingredient for improving vaccination coverage and sustaining progress against vaccine-preventable diseases. The opportunity is also explicitly tied to national priorities that were especially urgent in 2021, including responding to and preventing COVID-19 and strengthening resilience against other vaccine-preventable threats. It aligns with broader HHS strategic goals focused on protecting health in everyday settings (where people live, learn, work, and play) and supporting social and economic well-being across the lifespan.
The need for the program is justified by ongoing gaps in U.S. vaccination coverage and signs of weakening trust in vaccines and immunization systems. While childhood vaccination rates for many recommended vaccines are relatively high (often at or above 90 percent), the announcement points out that a substantial share of parents still refuse at least one recommended vaccine and many delay vaccines, which can leave children vulnerable for longer periods. It also notes that non-medical exemptions from school immunization requirements can reduce overall coverage and create pockets of susceptibility. For adolescents and adults, the problem is described as even more persistent, with coverage levels remaining comparatively low. The government argues that if this downward pressure on vaccine confidence continues, it could undermine decades of progress, increase the frequency and size of outbreaks, strain healthcare and public health systems, and even elevate national security risks by weakening population-level protection.
A key feature of the announcement is how it defines vaccine confidence, breaking it into three connected types of trust: confidence in the vaccine itself (its safety and effectiveness), confidence in the provider (the competence and reliability of the healthcare professional administering or recommending vaccination), and confidence in policy (trust that vaccine recommendations and schedules are made for appropriate reasons and in the public interest). Because these forms of trust directly influence individual decision-making, the opportunity emphasizes both understanding the local drivers of hesitancy and implementing interventions that can measurably improve confidence.
The initiative positions itself as an applied, community-facing complement to ongoing national work on vaccine confidence, including the National Vaccine Advisory Committee (NVAC) recommendations on determinants of vaccine confidence and strategies to strengthen it. While NVAC has provided evidence-informed guidance and policy-oriented recommendations, this funding opportunity highlights the continuing need for practical, on-the-ground solutions that bring together local partners to plan, implement, and evaluate approaches that work in real community settings. In other words, it is not only about messaging, but about building durable partnerships and testing methods that can be shown to improve trust and vaccination outcomes.
A major emphasis is expanding traditional immunization partnerships by engaging a wider set of stakeholders and organizations within local communities. The announcement specifically calls for partnering with minority-serving organizations and advocacy groups that work with populations experiencing lower vaccination rates or facing barriers to access and trust. Examples named in the opportunity include African American, Hispanic, and Native American communities, residents in rural areas, certain immigrant and refugee communities, and younger populations such as young adults, teens, and adolescents (in comparison to older adults and younger children). It also notes occupational groups such as medical assistants, suggesting an interest in reaching or mobilizing parts of the healthcare workforce that may be overlooked relative to other professions. The overall intent is to meet people where they are, using trusted local relationships, culturally informed strategies, and credible messengers to strengthen confidence and increase uptake.
From a funding and administrative standpoint, the opportunity is listed as Funding Opportunity Number NV VSR 21 001 under CFDA 93.344. It was posted July 9, 2021, with an original application deadline of August 17, 2021. The program anticipated making up to 8 awards, with an award ceiling of $125,000 per award. Eligibility is described broadly as "Others" with additional eligibility details referenced elsewhere in the full notice, which signals that the program may be intended for specific types of organizations beyond standard categories like state or local governments, such as nonprofits, community-based organizations, or other entities positioned to carry out partnership-based confidence-building work.
In summary, this grant opportunity funds partnership-driven, evidence-based, and locally tailored efforts to improve vaccine confidence, with a strong focus on communities and populations where vaccination rates lag and where trust in vaccines, providers, or policy may be strained. The federal goal is not only to increase vaccination coverage, including for COVID-19 and other routine immunizations, but to strengthen the underlying trust infrastructure that makes sustained, long-term protection possible.Apply for NV VSR 21 001
- The Department of Health and Human Services, Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "Promoting Vaccine Confidence in Local Communities through Partnership with Regional Health Offices" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.344.
- This funding opportunity was created on Jul 09, 2021.
- Applicants must submit their applications by Aug 17, 2021 No Explanation. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $125,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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