Opportunity Information: Apply for RFA CA 17 016

The Resource Center for the Consortium for Pancreatic Ductal Adenocarcinoma (PDAC) Translational Studies (U24) funding opportunity (RFA-CA-17-016) is a National Institutes of Health (NIH), Department of Health and Human Services grant that supports the creation of a centralized Resource Center to serve a larger multi-project research Consortium focused on PDAC and, specifically, the tumor microenvironment. The driving scientific purpose is to accelerate translational studies that can inform and enable the design of new immunotherapy approaches and rational combination interventions for pancreatic ductal adenocarcinoma, a cancer type widely recognized for its resistance to many existing therapies and its highly complex, immunosuppressive microenvironment.

This award uses a cooperative agreement mechanism (U24), which generally means the project is expected to be collaborative and interactive, with substantial involvement from the funding agency compared to a typical investigator-initiated grant. In practical terms, the Resource Center is meant to function as shared infrastructure and coordination capacity for the Consortium rather than as a standalone laboratory project. The Resource Center would typically be responsible for enabling and harmonizing Consortium activities, such as organizing communication and governance, supporting shared resources or services, standardizing data and materials across participating sites, and facilitating efficient collaboration so that findings can be compared, integrated, and translated more effectively. The overall aim is to reduce fragmentation across projects and speed progress toward clinically relevant immunotherapy and combination strategies in PDAC.

The opportunity falls under the broad activity areas of education and health and is associated with CFDA numbers 93.395 and 93.396. The FOA anticipated making a single award (ExpectedAwards: 1), emphasizing that the intent was to stand up one central Resource Center to serve the full Consortium. The maximum award amount listed is an annual ceiling of $350,000, indicating a modest budget relative to large research centers and reinforcing the idea that the Resource Center role is enabling, integrative, and service-oriented rather than funding multiple large research aims on its own.

Eligibility is broad and includes a wide range of public and private entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as listed); for-profit organizations (other than small businesses); and small businesses. This breadth suggests NIH was open to hosting the Resource Center at many kinds of institutions, as long as they could credibly deliver the coordination, infrastructure, and cross-institutional support the Consortium would require.

Key administrative details place the FOA in the 2016-2017 cycle: it was created on December 16, 2016, with an original closing date of March 7, 2017. The sponsor is NIH within HHS, and the category is discretionary funding. In summary, this FOA sought one awardee to build and operate a centralized Resource Center that would provide the organizational backbone and shared support functions for an NIH Consortium studying the PDAC tumor microenvironment, with the explicit translational objective of informing next-generation immunotherapy and combination treatment strategies for pancreatic cancer.

  • The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Resource Center for the Consortium for Pancreatic Ductal Adenocarcinoma (PDAC) Translational Studies (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.395, 93.396.
  • This funding opportunity was created on Dec 16, 2016.
  • Applicants must submit their applications by Mar 07, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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